Endocrine Abstracts

Introduction: Thyroid pathology is common in women of reproductive age. Evaluation of thyroid function is classically recommended in cases of recurrent abortion. The presence of dysthyroidism or antithyroid antibodies increases the risk of abortion. We report two observations of hypofertility related to thyroid pathology and discuss the therapeutic course.Case 1: A 33 year old woman was referred for etiological investigation of recurrent abortion. She pr...

IntroductionType 3 autoimmune polyendocrine syndrome (APS-3) is defined by the presence of an autoimmune thyroid disease and another autoimmune illness, excluding Addison’s disease; this is a frequent combination. Graves’ disease (GD) is an autoimmune disorder affecting approximately 0.5% of general population. It’s occurrence in autoimmune polyendocrine syndrome (APS) is less common than Hashimoto thyroiditis. The aim of our study was to ...

IntroductionAutoimmune Polyendocrine Syndrome (APS) is defined by the presence of 2 or more autoimmune induced endocrine failures in a single patient. There are 4 types of APS: type1 including chronic muco-cutaneous candidiasis, hypoparathyroidism, Addison disease (AD) and ectodermal dystrophy, APS type 2 and 3 containing autoimmune thyroide disease (AITD), type1 diabetes (DT1) with (type2) or without adrenal failure (type3) and type 4 not falling into t...

IntroductionVasculitis with antineutrophilic cytoplasmic antibodies (ANCA) has been reported in patients treated with anti-thyroid drugs, especially Propylthiouracil and exceptionally with benzylthiouracil (BTU). We present here a case of ANCA-anti-MPO-associated vasculitis related to BTU.Case presentationA 46 old women was treated with BTU during 18 months for Basedow’s...

IntroductionPatients with primary adrenal insufficiency (PAI) may have musculoskeletal symptoms. However, the association of such endocrinopathy with scleromyositis is extremely rare and has not been reported formerly to our acknowledge. Herein we report this association.Case reportA 32-years old female with one year history of profound global weakness was referred to internal department in April 2006, for su...

IntroductionThe ectopic parathyroid adenoma (EPTA) is the most common cause of failed parathyroid surgery. Most often localisations are intra-thymic and intra-mediastinal adenomas. We report a rare presentation of a symptomatic parathyroid adenoma located in ectopic retropharyngeal position diagnosed after surgical treatment of primary hyperparathyroidism (PHPT).ObsevationA 42-year-old female was referred to ...

IntroductionHypopituitarism is a rare condition defined by loss of pituitary function due to involvement of hypothalamus and/or pituitary gland by infiltrative diseases mainly sarcoidosis and Langerhans cell histiocytosis (LCH). Central diabetes insipidus is the most frequent manifestation of LCH (10–50%) and rarely in neuro-sarcoidois. Herein, we describe 2cases of hypopituitarism due to neuro-sarcoidosis and LCH.Case 1<p...